Survey of Clinical Laboratory Practices for 2015 Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea
Identifieur interne : 001560 ( Main/Exploration ); précédent : 001559; suivant : 001561Survey of Clinical Laboratory Practices for 2015 Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea
Auteurs : Mi-Kyung Lee [Corée du Sud] ; Sinyoung Kim [Corée du Sud] ; Mi-Na Kim [Corée du Sud] ; Oh Joo Kweon [Corée du Sud] ; Yong Kwan Lim [Corée du Sud] ; Chang-Seok Ki [Corée du Sud] ; Jae-Seok Kim [Corée du Sud] ; Moon-Woo Seong [Corée du Sud] ; Heungsup Sung [Corée du Sud] ; Dongeun Yong [Corée du Sud] ; Hyukmin Lee [Corée du Sud] ; Jong-Rak Choi [Corée du Sud] ; Jeong-Ho Kim [Corée du Sud]Source :
- Annals of Laboratory Medicine [ 2234-3806 ] ; 2015.
Descripteurs français
- KwdFr :
- ARN viral (analyse), Coronavirus du syndrome respiratoire du Moyen-Orient (génétique), Coronavirus du syndrome respiratoire du Moyen-Orient (isolement et purification), Enquêtes et questionnaires, Expectoration (virologie), Flambées de maladies, Humains, Infections à coronavirus (diagnostic), Infections à coronavirus (virologie), Infections à coronavirus (épidémiologie), Réaction de polymérisation en chaine en temps réel, République de Corée (épidémiologie), Services de laboratoire d'analyses médicales (normes), Techniques de laboratoire clinique (), Techniques de laboratoire clinique (instrumentation).
- MESH :
- analyse : ARN viral.
- diagnostic : Infections à coronavirus.
- génétique : Coronavirus du syndrome respiratoire du Moyen-Orient.
- isolement et purification : Coronavirus du syndrome respiratoire du Moyen-Orient.
- normes : Services de laboratoire d'analyses médicales.
- virologie : Expectoration, Infections à coronavirus.
- épidémiologie : Infections à coronavirus, République de Corée, Techniques de laboratoire clinique.
- Enquêtes et questionnaires, Flambées de maladies, Humains, Réaction de polymérisation en chaine en temps réel, Techniques de laboratoire clinique.
English descriptors
- KwdEn :
- Clinical Laboratory Services (standards), Clinical Laboratory Techniques (instrumentation), Clinical Laboratory Techniques (methods), Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Coronavirus Infections (virology), Disease Outbreaks, Humans, Middle East Respiratory Syndrome Coronavirus (genetics), Middle East Respiratory Syndrome Coronavirus (isolation & purification), RNA, Viral (analysis), Real-Time Polymerase Chain Reaction, Republic of Korea (epidemiology), Sputum (virology), Surveys and Questionnaires.
- MESH :
- chemical , analysis : RNA, Viral.
- diagnosis : Coronavirus Infections.
- epidemiology : Coronavirus Infections, Republic of Korea.
- genetics : Middle East Respiratory Syndrome Coronavirus.
- instrumentation : Clinical Laboratory Techniques.
- isolation & purification : Middle East Respiratory Syndrome Coronavirus.
- methods : Clinical Laboratory Techniques.
- standards : Clinical Laboratory Services.
- virology : Coronavirus Infections, Sputum.
- Disease Outbreaks, Humans, Real-Time Polymerase Chain Reaction, Surveys and Questionnaires.
Abstract
It is crucial to understand the current status of clinical laboratory practices for the largest outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infections in the Republic of Korea to be well prepared for future emerging infectious diseases.
We conducted a survey of 49 clinical laboratories in medical institutions and referral medical laboratories. A short questionnaire to survey clinical laboratory practices relating to MERS-CoV diagnostic testing was sent by email to the directors and clinical pathologists in charge of the clinical laboratories performing MERS-CoV testing. The survey focused on testing volume, reporting of results, resources, and laboratory safety.
A total of 40 clinical laboratories responded to the survey. A total of 27,009 MERS-CoV real-time reverse transcription PCR (rRT-PCR) tests were performed. Most of the specimens were sputum (73.5%). The median turnaround time (TAT) was 5.29 hr (first and third quartile, 4.11 and 7.48 hr) in 26 medical institutions. The median TAT of more than a half of the laboratories (57.7%) was less than 6 hr. Many laboratories were able to perform tests throughout the whole week. Laboratory biosafety preparedness included class II biosafety cabinets (100%); separated pre-PCR, PCR, and post-PCR rooms (88.6%); negative pressure pretreatment rooms (48.6%); and negative pressure sputum collection rooms (20.0%).
Clinical laboratories were able to quickly expand their diagnostic capacity in response to the 2015 MERS-CoV outbreak. Our results show that clinical laboratories play an important role in the maintenance and enhancement of laboratory response in preparation for future emerging infections.
Url:
DOI: 10.3343/alm.2016.36.2.154
PubMed: 26709263
PubMed Central: 4713849
Affiliations:
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xml:lang="en" level="a" type="main">Survey of Clinical Laboratory Practices for 2015 Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea</title><author><name sortKey="Lee, Mi Kyung" sort="Lee, Mi Kyung" uniqKey="Lee M" first="Mi-Kyung" last="Lee">Mi-Kyung Lee</name><affiliation wicri:level="3"><nlm:aff id="A1">Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kim, Sinyoung" sort="Kim, Sinyoung" uniqKey="Kim S" first="Sinyoung" last="Kim">Sinyoung Kim</name><affiliation wicri:level="3"><nlm:aff id="A2">Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kim, Mi Na" sort="Kim, Mi Na" uniqKey="Kim M" first="Mi-Na" last="Kim">Mi-Na Kim</name><affiliation wicri:level="3"><nlm:aff id="A3">Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kweon, Oh Joo" sort="Kweon, Oh Joo" uniqKey="Kweon O" first="Oh Joo" last="Kweon">Oh Joo Kweon</name><affiliation wicri:level="3"><nlm:aff id="A1">Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Lim, Yong Kwan" sort="Lim, Yong Kwan" uniqKey="Lim Y" first="Yong Kwan" last="Lim">Yong Kwan Lim</name><affiliation wicri:level="3"><nlm:aff id="A1">Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Ki, Chang Seok" sort="Ki, Chang Seok" uniqKey="Ki C" first="Chang-Seok" last="Ki">Chang-Seok Ki</name><affiliation wicri:level="3"><nlm:aff id="A4">Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kim, Jae Seok" sort="Kim, Jae Seok" uniqKey="Kim J" first="Jae-Seok" last="Kim">Jae-Seok Kim</name><affiliation wicri:level="3"><nlm:aff id="A5">Department of Laboratory Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Seong, Moon Woo" sort="Seong, Moon Woo" uniqKey="Seong M" first="Moon-Woo" last="Seong">Moon-Woo Seong</name><affiliation wicri:level="3"><nlm:aff id="A6">Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Sung, Heungsup" sort="Sung, Heungsup" uniqKey="Sung H" first="Heungsup" last="Sung">Heungsup Sung</name><affiliation wicri:level="3"><nlm:aff id="A4">Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Yong, Dongeun" sort="Yong, Dongeun" uniqKey="Yong D" first="Dongeun" last="Yong">Dongeun Yong</name><affiliation wicri:level="3"><nlm:aff id="A2">Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Lee, Hyukmin" sort="Lee, Hyukmin" uniqKey="Lee H" first="Hyukmin" last="Lee">Hyukmin Lee</name><affiliation wicri:level="1"><nlm:aff id="A7">Department of Laboratory Medicine, Catholic Kwandong University College of Medicine, Incheon, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine, Catholic Kwandong University College of Medicine, Incheon</wicri:regionArea><wicri:noRegion>Incheon</wicri:noRegion></affiliation></author><author><name sortKey="Choi, Jong Rak" sort="Choi, Jong Rak" uniqKey="Choi J" first="Jong-Rak" last="Choi">Jong-Rak Choi</name><affiliation wicri:level="3"><nlm:aff id="A2">Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul</wicri:regionArea><placeName><settlement type="city">Séoul</settlement><region type="capital">Région capitale de Séoul</region></placeName></affiliation></author><author><name sortKey="Kim, Jeong Ho" sort="Kim, Jeong Ho" uniqKey="Kim J" first="Jeong-Ho" last="Kim">Jeong-Ho Kim</name><affiliation wicri:level="3"><nlm:aff id="A2">Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Corée du Sud</country><wicri:regionArea>Department of Laboratory Medicine, Yonsei University College of 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(instrumentation)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>ARN viral</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Republic of Korea</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Clinical Laboratory Techniques</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Middle East Respiratory Syndrome Coronavirus</term></keywords><keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr"><term>Coronavirus du syndrome respiratoire du Moyen-Orient</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Clinical Laboratory Techniques</term></keywords><keywords scheme="MESH" qualifier="normes" xml:lang="fr"><term>Services de laboratoire d'analyses médicales</term></keywords><keywords scheme="MESH" qualifier="standards" xml:lang="en"><term>Clinical Laboratory Services</term></keywords><keywords scheme="MESH" qualifier="virologie" xml:lang="fr"><term>Expectoration</term><term>Infections à coronavirus</term></keywords><keywords scheme="MESH" qualifier="virology" xml:lang="en"><term>Coronavirus Infections</term><term>Sputum</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>République de Corée</term><term>Techniques de laboratoire clinique</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Disease Outbreaks</term><term>Humans</term><term>Real-Time Polymerase Chain Reaction</term><term>Surveys and Questionnaires</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Enquêtes et questionnaires</term><term>Flambées de maladies</term><term>Humains</term><term>Réaction de polymérisation en chaine en temps réel</term><term>Techniques de laboratoire clinique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>It is crucial to understand the current status of clinical laboratory practices for the largest outbreak of Middle East respiratory syndrome coronavirus (MERS-CoV) infections in the Republic of Korea to be well prepared for future emerging infectious diseases.</p></sec><sec><title>Methods</title><p>We conducted a survey of 49 clinical laboratories in medical institutions and referral medical laboratories. A short questionnaire to survey clinical laboratory practices relating to MERS-CoV diagnostic testing was sent by email to the directors and clinical pathologists in charge of the clinical laboratories performing MERS-CoV testing. The survey focused on testing volume, reporting of results, resources, and laboratory safety.</p></sec><sec><title>Results</title><p>A total of 40 clinical laboratories responded to the survey. A total of 27,009 MERS-CoV real-time reverse transcription PCR (rRT-PCR) tests were performed. Most of the specimens were sputum (73.5%). The median turnaround time (TAT) was 5.29 hr (first and third quartile, 4.11 and 7.48 hr) in 26 medical institutions. The median TAT of more than a half of the laboratories (57.7%) was less than 6 hr. Many laboratories were able to perform tests throughout the whole week. Laboratory biosafety preparedness included class II biosafety cabinets (100%); separated pre-PCR, PCR, and post-PCR rooms (88.6%); negative pressure pretreatment rooms (48.6%); and negative pressure sputum collection rooms (20.0%).</p></sec><sec><title>Conclusions</title><p>Clinical laboratories were able to quickly expand their diagnostic capacity in response to the 2015 MERS-CoV outbreak. Our results show that clinical laboratories play an important role in the maintenance and enhancement of laboratory response in preparation for future emerging infections.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Cowling, Bj" uniqKey="Cowling B">BJ Cowling</name></author><author><name sortKey="Park, M" uniqKey="Park M">M Park</name></author><author><name sortKey="Fang, Vj" uniqKey="Fang V">VJ Fang</name></author><author><name sortKey="Wu, P" uniqKey="Wu P">P Wu</name></author><author><name sortKey="Leung, Gm" uniqKey="Leung G">GM Leung</name></author><author><name sortKey="Wu, Jt" uniqKey="Wu J">JT Wu</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hayden, Rt" uniqKey="Hayden R">RT Hayden</name></author><author><name sortKey="Wick, Mt" uniqKey="Wick M">MT Wick</name></author><author><name sortKey="Rodriguez, Ab" uniqKey="Rodriguez A">AB Rodriguez</name></author><author><name sortKey="Caliendo, Am" uniqKey="Caliendo A">AM Caliendo</name></author><author><name sortKey="Mitchell, Mj" uniqKey="Mitchell M">MJ Mitchell</name></author><author><name sortKey="Ginocchio, Cc" uniqKey="Ginocchio C">CC Ginocchio</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sullivan, Sj" uniqKey="Sullivan S">SJ Sullivan</name></author><author><name sortKey="Jacobson, Rm" uniqKey="Jacobson R">RM Jacobson</name></author><author><name sortKey="Dowdle, Wr" uniqKey="Dowdle W">WR Dowdle</name></author><author><name sortKey="Poland, Ga" uniqKey="Poland G">GA Poland</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Crawford, Jm" uniqKey="Crawford J">JM Crawford</name></author><author><name sortKey="Stallone, R" uniqKey="Stallone R">R Stallone</name></author><author><name sortKey="Zhang, F" uniqKey="Zhang F">F Zhang</name></author><author><name sortKey="Gerolimatos, M" uniqKey="Gerolimatos M">M Gerolimatos</name></author><author><name sortKey="Korologos, Dd" uniqKey="Korologos D">DD Korologos</name></author><author><name sortKey="Sweetapple, C" uniqKey="Sweetapple C">C Sweetapple</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lautenbach, E" uniqKey="Lautenbach E">E Lautenbach</name></author><author><name sortKey="Saint, S" uniqKey="Saint S">S Saint</name></author><author><name sortKey="Henderson, Dk" uniqKey="Henderson D">DK Henderson</name></author><author><name sortKey="Harris, Ad" uniqKey="Harris A">AD Harris</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lee, Wg" uniqKey="Lee W">WG Lee</name></author><author><name sortKey="Kwak, Ys" uniqKey="Kwak Y">YS Kwak</name></author><author><name sortKey="Lee, Dh" uniqKey="Lee D">DH Lee</name></author><author><name sortKey="Hwang, Ys" uniqKey="Hwang Y">YS Hwang</name></author><author><name sortKey="Lee, Kn" uniqKey="Lee K">KN Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oboho, Ik" uniqKey="Oboho I">IK Oboho</name></author><author><name sortKey="Tomczyk, Sm" uniqKey="Tomczyk S">SM Tomczyk</name></author><author><name sortKey="Al Asmari, Am" uniqKey="Al Asmari A">AM Al-Asmari</name></author><author><name sortKey="Banjar, Aa" uniqKey="Banjar A">AA Banjar</name></author><author><name sortKey="Al Mugti, H" uniqKey="Al Mugti H">H Al-Mugti</name></author><author><name sortKey="Aloraini, Ms" uniqKey="Aloraini M">MS Aloraini</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tartari, E" uniqKey="Tartari E">E Tartari</name></author><author><name sortKey="Allegranzi, B" uniqKey="Allegranzi B">B Allegranzi</name></author><author><name sortKey="Ang, B" uniqKey="Ang B">B Ang</name></author><author><name sortKey="Calleja, N" uniqKey="Calleja N">N Calleja</name></author><author><name sortKey="Collignon, P" uniqKey="Collignon P">P Collignon</name></author><author><name sortKey="Hopman, J" uniqKey="Hopman J">J Hopman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Breban, R" uniqKey="Breban R">R Breban</name></author><author><name sortKey="Riou, J" uniqKey="Riou J">J Riou</name></author><author><name sortKey="Fontanet, A" uniqKey="Fontanet A">A Fontanet</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pereyaslov, D" uniqKey="Pereyaslov D">D Pereyaslov</name></author><author><name sortKey="Rosin, P" uniqKey="Rosin P">P Rosin</name></author><author><name sortKey="Palm, D" uniqKey="Palm D">D Palm</name></author><author><name sortKey="Zeller, H" uniqKey="Zeller H">H Zeller</name></author><author><name sortKey="Gross, D" uniqKey="Gross D">D Gross</name></author><author><name sortKey="Brown, Cs" uniqKey="Brown C">CS Brown</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Sousa, R" uniqKey="De Sousa R">R de Sousa</name></author><author><name sortKey="Reusken, C" uniqKey="Reusken C">C Reusken</name></author><author><name sortKey="Koopmans, M" uniqKey="Koopmans M">M Koopmans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Meltzer, Mi" uniqKey="Meltzer M">MI Meltzer</name></author><author><name sortKey="Mcneill, Km" uniqKey="Mcneill K">KM McNeill</name></author><author><name sortKey="Miller, Jd" uniqKey="Miller J">JD Miller</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Corée du Sud</li></country><region><li>Région capitale de Séoul</li></region><settlement><li>Séoul</li></settlement></list><tree><country name="Corée du Sud"><region name="Région capitale de Séoul"><name sortKey="Lee, Mi Kyung" sort="Lee, Mi Kyung" uniqKey="Lee M" first="Mi-Kyung" last="Lee">Mi-Kyung Lee</name></region><name sortKey="Choi, Jong Rak" sort="Choi, Jong Rak" uniqKey="Choi J" first="Jong-Rak" last="Choi">Jong-Rak Choi</name><name sortKey="Ki, Chang Seok" sort="Ki, Chang Seok" uniqKey="Ki C" first="Chang-Seok" last="Ki">Chang-Seok Ki</name><name sortKey="Kim, Jae Seok" sort="Kim, Jae Seok" uniqKey="Kim J" first="Jae-Seok" last="Kim">Jae-Seok Kim</name><name sortKey="Kim, Jeong Ho" sort="Kim, Jeong Ho" uniqKey="Kim J" first="Jeong-Ho" last="Kim">Jeong-Ho Kim</name><name sortKey="Kim, Mi Na" sort="Kim, Mi Na" uniqKey="Kim M" first="Mi-Na" last="Kim">Mi-Na Kim</name><name sortKey="Kim, Sinyoung" sort="Kim, Sinyoung" uniqKey="Kim S" first="Sinyoung" last="Kim">Sinyoung Kim</name><name sortKey="Kweon, Oh Joo" sort="Kweon, Oh Joo" uniqKey="Kweon O" first="Oh Joo" last="Kweon">Oh Joo Kweon</name><name sortKey="Lee, Hyukmin" sort="Lee, Hyukmin" uniqKey="Lee H" first="Hyukmin" last="Lee">Hyukmin Lee</name><name sortKey="Lim, Yong Kwan" sort="Lim, Yong Kwan" uniqKey="Lim Y" first="Yong Kwan" last="Lim">Yong Kwan Lim</name><name sortKey="Seong, Moon Woo" sort="Seong, Moon Woo" uniqKey="Seong M" first="Moon-Woo" last="Seong">Moon-Woo Seong</name><name sortKey="Sung, Heungsup" sort="Sung, Heungsup" uniqKey="Sung H" first="Heungsup" last="Sung">Heungsup Sung</name><name sortKey="Yong, Dongeun" sort="Yong, Dongeun" uniqKey="Yong D" first="Dongeun" last="Yong">Dongeun Yong</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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